Petroclival meningiomas represent the most complex lesions in skull base surgery, being closely related to critical neurovascular structures. The combined petrosal approach allows a wide exposure of the petroclival region and provides multiple angles of attack, limiting brain retraction. The authors present the case of a 54-year-old man with a large left petroclival meningioma […]
Abstract Background: Management of advanced chordomas remains delicate considering their insensitivity to chemotherapy. Homozygous deletion of the regulatory gene CDKN2A has been described as the most frequent genetic alteration in chordomas and may be considered as a potential theranostic marker. Here, we evaluated the tumor efficacy of the CDK4/6 inhibitor palbociclib, as well as […]
This book aims to give the state-of-the-art of intraoperative brain function mapping for resection of brain tumors in awake conditions, and to become a reference for acquiring the fundamental expertise necessary to select the right intraoperative task at the right time of the surgery. The chapters, all focused on a specific brain function, are […]
L’ouvrage marque le 50ème anniversaire de la première description de la dysplasie de Taylor, qui a révolutionné le monde de l’épilepsie et retrace l’histoire de l’évolution des concepts dans le monde de la recherche clinique et fondamentale. Les plus grands experts internationaux en épileptologie, neurophysiologie, neuropathologie, génétique, imagerie et neurochirurgie, ont conçu cet ouvrage […]